Methyl Folate - 5-MTHF

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Methyl Folate - 5-MTHF

Methyl Folate | Select Balance Supplements

Methyl Folate is the most active form of folic acid. Excellent for those that have trouble converting folic acid into its active form. We use only fully stabilized Quatrefolate, the best form available.

Methyl folate may be helpful for a range of health concerns, including:

  • Mood disorders – Methyl folate represents a better option for patients due to its greater bioavailability and lack of side effects.
  • Homocysteine reducer – A folate enriched diet, or supplementation with bioavailable methyl folate has been shown to lower homocysteine levels, an amino acid associated with a higher risk of cardiovascular problems.
  • Diabetic peripheral neuropathy – A randomized, double-blind, placebo-controlled trial found that patients with diabetic neuropathy experienced quality of life improvements with methyl folate.
  • Skin disorders – A recent 2013 study found high proportions of methyl folate in the epidermis, even as serum folate levels dropped. This has suggested it as a potential UV skin protectant and an option for skin conditions such as psoriasis.

Dosage: Take 1 capsule daily with food or as recommended by your practitioner

Supplement Facts


What is the difference between Folic Acid and Folate (Methyl Folate)? Folic acid refers to the oxidized synthetic (made by chemical synthesis, especially to imitate a natural product) compound used in dietary supplements and food fortification, whereas folate refers to the various tetrahydrofolate derivatives naturally found in food. A high intake of folic acid, may result in unnatural levels of unmetabolized folic acid entering the systemic circulation which can lead to adverse events such as cancer, cognitive decline and more.

Folate in the form of Methyl Folate is essential for health.

Excellent sources of dietary folate include vegetables such as romaine lettuce, spinach, asparagus, turnip greens, mustard greens, parsley, collard greens, broccoli, cauliflower, beets, and lentils. Some of the best sources are calf’s liver and chicken liver.

Manufactured in a US FDA inspected facility. GMP Compliant. 
‡ These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.